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    Today, we live in an uncertain world. We can not predict what will happen in the next second. If yo
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    u can, then you must me something else other than a living being. Today, we are constantly terrified
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    by the uncertainty of the next moment.

    As I write this article, I don’t actually know what will hap
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    en the next moment. A new inventory in technology may jeopardize my current work as a typist. As I t
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ype, I do so with fear because I don’t know weather my boss will be coming back the next moment with
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    robot that will type more effective, accurate and efficiently than I do. If such happens, that means
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    that I will lose my current job as a typist.

    I hope I am not the only one that is engulfed with pho
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ia when it comes to sustaining ones current work. I thank God for giving man the ability to adapt an
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    d change. How will you feel if a robot is waiting to replace you in your current work? Do you think
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    t is not possible? Please don’t think that it is not possible.

    By the year 2050, I believe the world
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    will be a digital village. With the pace at which electronic books is replacing paper books, I know
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    that one day in future, the paper books will become extinct. Now, when paper books become extinct,
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    hat do you think will be the faith of book publishers? By the year 2050, news papers and magazines w
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ill be read on an electronic device which may invade the world in the next few seconds. When this hap
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ens, what will the newspaper vendors do to sustain life? A big question for us to answer.

    How prepar
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ed are you for such an eventuality that will make you unemployed. Think and act now before such even
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    uality befalls you.

    Few days ago, I was discussing with a medical student, who I asked what he will
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    do if sickness becomes a history in the few years to come. He was horrified at such question? He dec
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ared me an enemy with out waste of time.

    Just think of how sustainable your present Job will be in t
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    he next moment. Any thing can happen at any time. Have a nice moment as you give it a second taught


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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