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Forums are great places for like minded people to get together to discuss their chosen topic of interest. There are thousands of forums in cyberspace and each forum often has thousands of individual members. All would be fine a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nd dandy in these often happy and friendly communities except for one big bugbear. Spammers like to join forums and then post links to their often unsavoury websites. The forum Administrators and moderators usually jump on them

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and delete their posts almost as quickly as they are submitted, so what do spammers think they actually get out of posting in forums? Let’s have a look at some reasons why they do it.

First of all, let’s define what a forum s

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

pammer actually is. A forum spammer is a person or in some cases a cyber robot that signs up for membership of a forum. The first thing they usually do is edit their profile (the section where they can enter certain personal de

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

tails) and include a link to their website. They will often use an unintelligible user name, the name that they will be known by in the forum. They will usually hide behind a dynamic IP address. Once their membership has been a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

cepted by the forum, they will often create a single post or sometimes multiple posts that contain either one or more links to their website or affiliate sites and sometimes pornographic pictures linking back to their porn site

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

or sites.

Now let’s surmise why they do these things.

First, by creating a profile, they obtain what is known as a “back-link” to their website, which is desirable in the endless struggle to achieve a good search engine rank

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ing.

Second, they use a strange user name because they will often sign up to the same forum multiple times using different names in order to get past the forum’s security systems and to try to fool the forum administrator. The

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y also use a dynamic IP address for the same reason. It’s all to make them look like a new member who hasn’t joined before.

Thirdly, the use of a dynamic IP address gives them a certain amount of anonymity by cloaking their tr

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ue IP address in order to avoid being traced to their hosting company and being reported for their antisocial activities and possibly being banned.

Lastly, they include links or pictures in their posts in the forum in the beli

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

f that the forum members will be so interested that they will click those links and visit their website.

Now let’s look at the flaws in that mode of thinking and how forum administrators can use these flaws to rout out the spa

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

mmers and stop them in their tracks.

First, by creating a profile including a link to their website upon joining a forum they immediately alert the forum administrator that the new member may be a spammer. Administrators who a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

re on the ball will immediately delete the link to this new member’s website in their profile, so they have lost their precious back-link straight away.

Secondly, by using a strange or unintelligible user name the new member a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lso alerts the savvy forum administrator that they are most likely a spammer and they not only lose their back-link in their profile, but get their username banned before they get a chance to create a post with their links.

Th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

irdly, a dynamic IP address will show up in the spammer post if they got past the first two points, but if the forum administrator catches them while they are online, their true IP address can be obtained and used to report the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to their host.

Lastly, active forum members are very protective of their forum community as they like the nice, friendly atmosphere and want to keep it that way. So any spam posts are almost never read by the members and they

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

will certainly never click on the links contained in them, so the spammer is doing all that work for absolutely nothing more than to irritate the members. The forum moderators are often very quick to delete spam posts anyway,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

so the members rarely ever get to see them in any case.

So that leads us full circle in asking the question, “What do spammers get out of posting in forums?”

The answer, in most cases is very little. They lose their back-link

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s almost as soon as they’ve created them and their posts are treated like something you’d just scraped off your shoe and are deleted almost as soon as they are posted. Which leads us to another, even more poignant question, “Wh

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

y do they do it?”

They obviously believe, in their own little worlds, that they are promoting their wares to great effect, when the reality is they are just wasting their time and irritating a whole lot of people along the way

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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