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  • Useful Advices - Automatic Positive Thoughts (APTs) Rule!

    Are You Sure?

    People are ‘unsure’ of their place, and who-and-what they are. Confidence is an assumption – not a tangible entity like a leg. Is self-confidence a product of your bank-account, a decade or two of success?

    Real as a Right-Sided-Stroke
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

    After fifteen-years as Division Vice-President overseeing 1,200 executives, graduating from MIT with a Ph.D, and earned wealth with all its support systems. He smiled comically as he shared his deepest secret with a stranger…

    “Every day I come to wo
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    rk – that’s fifteen-years – I wait to hear they figured-it-out – that I’m faking it, and know-nothing. No, it didn’t happen today – but probably tomorrow – maybe not. Okay, I’ll stick it out for anotherday – I still got ‘em fooled – aint that the limit?
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.



    How can you relax and enjoy your success when you fear your competency? Where does confidence come from? Is it genetic and hardwired, or can you buy it at Walmart?

    Self-Confidence is not a ‘given’, it requires daily reinforcement at both your cons
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    cious and non-conscious mind - or its shoots-its-wad and silently departs like Hurricane Rita.

    You’ve Heard of ANTs – ‘Automatic-Negative-Thoughts

    Psychologists estimate we have two-hundred different ANTs living in our mind to advise us about our tal
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    nts, character, and personal-worth. Ninety-eight percent of the time they automatically assure us we stink, are a no-talent, and are fooling-the-public.

    Read the lips of the Australian tennis-pro playing for the title – who smashed the ball into the ne
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    t – “You stupid, no-good S.O.B. You… *&$!!”, he says to himself.

    His blood boils over, and he can hardly breathe, but it goes on for up to sixty-seconds. Guess happens to him on the next serve - in that state-of-mind? Right – he goofs again, and takes
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    that as evidence the ANTs are right! Okay – what’s your first-reaction to falling-flat on your fact? You need a new strategy that empowers you – not insults you when you stumble.

    The ANTs Got Him

    The first step is having ‘Two-Minute-Strategies™’ to
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    make self-esteem and personal-power automatic - and run on auto-pilot.

    Know these Two-Minutes-Strategies and punch ‘illegitimate’ self-doubt – in the snout.

    “Breathe-Stretch-Shake – Let-it-Go!”

    First, the name – MASE, a superstar Rapper, released a l
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    yric in 2005 on his “Welcome-Back” album called – ‘Breathe-Stretch-Shake and Let-it-go’.

    Goal for us: annihilate the nasties from your mind, and alert the Big-Five senses to pay-attention and concentrate on the work-at-hand.

    One-more-once – when you w
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    nt to clear your head, focus on being productive – wake-up! your mind-and-body (not before going to sleep) – use ‘Breathe-Stretch-Shake – Let-it-Go!’

    Personally - it should be a requirement every 90-minutes because we wind-down every one-and-a-half hou
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    rs. That’s a scientific-fact, not an urban-myth.

    This exercise takes no more than ninety (90) seconds!

    1. Stand up – yes, that requires a decision.
    2. Close your eyes – do it when you are in private.
    3. Visualize your heart, and place your r
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ight-hand in the center of your chest.
    4. Take a diaphragmatic breath (deeply inhale), and count to seven-beats - one-one-thousand, two-one-thousand, three-one…etc.
    5. Switch hands and place your left-hand a hand-span above your navel (belly
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    -button, umbilicus), and visualize your belly-button.
    6. Hold that inhalation to a count of ten-beats – (seconds) while simultaneously visualizing your belly-button.
    7. Exhale s-l-o-w-l-y to a count of seven-beats, and open your eyes.
    8
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    . Now – stretch out your arms and legs – and really s-t-r-e-t-c-h.
    9. Shake-your-body vigorously – starting from your head and working down to your feet.
    10. Last – and 50% of your grade – Slap-your-hand-down on a flat-surface, and shout-out
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    if it is appropriate, or self-talk – enthusiastically … “Let-it-Go!”

    “But What’s the meaning of All This?”

    We intellectuals – left-brain dominant – successful folk – spend 95% of consciousness analyzing the ‘why?’ of stuff. Just this once – just-do-
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    it! - and focus on the ‘how’ of things. The results are instantaneous – your brain gets a 12% jolt of oxygen and glucose, and disposes of excess carbon dioxide.

    You’re awake and kicking – and ready to ‘concentrate’ on whatever you choose.

    Conduct you
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    r own experiment – ‘Breathe-Stretch-Shake – Let-it-Go!’ - and discover your power of focus-and-attention – particularly after you notice yourself winding-down to a snail.

    “But when do I do this exercise…and how do I…?”

    Who is the Boss of You?

    Use you
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    r volition – c-h-o-o-s-e, make decisions. Resign from being a ‘grunt’, and be the commander-in-chief. It’s your life or go ask your Mama if this is worth learning. Confidence means ‘with-trust’, and leads to self-assurance through belief, when you t
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ake command of your mind-and-body.

    See ya,

    copyright © 2005
    H. Bernard Wechsler
    www.speedlearning.org
    hbw@speedlearning.org
    -----------------------------------------------------------------------------------------------------------


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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