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    Factoring of receivables is an arrangement whereby a company sells its accounts receivables to another compa
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ny (banks and other institutions) that specializes in buying them and obtains the necessary financial accomm
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    odation. It is the most popular method of short-term financing in the US. Factoring offers the following adv
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    antages: relief to manufacturers and sellers from the bother of collection of book debts, saving in time and
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    man-power required for debt collection, and last but not the least, adequate and better source of financing
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    .

    The factoring institutions render the following functions: Credit recording- that involves maintenance of
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    debtor’s ledgers, collection schedules etc. Secondly, there is Credit administration that includes the coll
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ection of debts. Thirdly, there is credit financing, whereby the factor advances money against receivables.
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    Finally, there is finance and business information wherein advices are given to customers on current trends
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    and challenges.

    Commercial paper is an important money market instrument, which is in the form of unsecured
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    promissory notes issued by firms to raise short-term funds. Certain conditions are to be satisfied before t
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    he issue of commercial paper. Permission should also be obtained from the credit rating agencies. Commercial
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    papers are issued for a period ranging from 3 months to 6 months. Commercial paper offers alternative sour
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ce of raising short-term finance, helpful in times of tight bank credit and is a cheaper source of finance.
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen

    Term loans are those loans that are extended for a specific period ranging from 1 to 15 years. Medium term
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    loans are extended for a period of 5 years and long-term loans are granted for a period of 15 years. Term lo
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ans are granted for establishment, renovation, expansion and modernization of industrial units as well as me
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    eting the requirements of core working capital and for repayment of bonds and preference shares. Term loans
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    are usually secured. They have either a fixed or a floating charge against the assets of the company. They
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    are granted on the basis of a formal agreement, which contains the terms, and a condition of providing loans


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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