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Useful Advices - Silk Yarn And Its Production Process
Silk fibre is the most beautiful natural fibre to be found by the human civilization. Well speaking of the histo
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ry of this special fibre, all credit goes to the Chinese Empress three millennia before when she thought of doin
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
some good for her people. Her act of doing well for the Chinese has blessed the world with such a wonderful fib
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
e. Silk Yarns and apparels are in good demand all through out the year producing good textile business. China is
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
the largest producer and exporter of silk globally. The silk produced in china is popular by the name ‘China Sil
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
’ prefixes to all products.
Now let’s look at the traditional production process of the cultivated silk fibre.
Now let’s look at the traditional production process of the cultivated silk fibre.
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
he natural habitat for a silk worm is the mulberry tree which id cultivated in large numbers for the breeding of
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
the silk worm. The production of cultivated silk is known as sericulture.
1. Hatching of Eggs: The silk moth la
1. Hatching of Eggs: The silk moth la
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
s eggs. When the eggs hatch the caterpillars are fed mulberry leaves. When the silkworms are about 35 days old t
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ey are 10,000 times heavier than when they hatched. They are now ready to spin a silk cocoon.
2. Silk productio
2. Silk productio
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
by worm: The silk is produced in two glands in the silkworm’s head and the forced out in liquid form through op
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
nings called spinnerets. The silk solidifies when it comes in contact with the air. The silkworm spins approxima
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ely 1 mile of filament and completely encloses itself in a cocoon in about 2 or three days.
3. Transition of th
3. Transition of th
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
worm: The silkworm then goes through stages and changes into a moth; however, the silkworm is usually killed wi
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
h heat before it reaches this stage. The silkworms are killed because once they reach the moth stage; the moth s
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
cretes a fluid to dissolve the silk so it can emerge from the cocoon. This damages the cocoon and the silk and t
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
e silk then becomes a lower quality. Some silkworms are allowed to live to be used for breeding.
4. Raw Fibre O
4. Raw Fibre O
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
tained: The silk is obtained from the undamaged cocoons by brushing the cocoon to find the outside ends of the f
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
lament. The silk filaments are then wound on a reel. One cocoon contains approximately 1,000 yards of silk filam
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
nt. The silk at this stage is known as raw silk. A yarn can now be formed by combining several filaments of silk
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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